Martin Sjöström

This study uses CRISPR screens to identify PTGES3 as a novel modulator of AR protein levels and function in prostate cancer, showing its role in therapy resistance.

This study identifies canonical AREs as tumor suppressive regulatory elements in prostate cancer, showing their reactivation can induce death in AR+ cancer cells and is linked to better prognosis.

This study identifies a gastrointestinal gene expression phenotype in metastatic castration-resistant prostate cancer that correlates with reduced response to androgen receptor inhibitors.

The paper improves a proteogenomics workflow to reveal molecular phenotypes linked to breast cancer appearance, showing differences in protein networks and biomarker abundance.