Author

Anthony R. Monte Carlo

Thomas Jefferson UniversityORCID 0000-0002-9472-3271Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Anna PluciennikiD· 2 shared Ashutosh S. PhadteiD· 2 shared Mayuri BhatiaiD· 2 shared Sarah BarndtiD· 2 shared Anna Lakhina· 1 shared Chun-Feng David HouiD· 1 shared F. LiiD· 1 shared Rong YangiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 32 mutual co-author links

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2 shared papersBiochemistry

Anna PluciennikORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

DNA extrusion size determines pathway choice during CAG repeat expansion

Mayuri Bhatia, Ashutosh S. Phadte, Anna Lakhina, Anthony R. Monte Carlo, Sarah Barndt, Anna Pluciennik

The paper shows that DNA extrusion size determines whether triplet repeats are expanded or stabilized through competition between FAN1 and MutSβ repair pathways.

Nucleic Acids Research · Nov 25, 2025Peer-reviewedBiochemistry

Structural and molecular basis of FAN1 defects in promoting Huntington's disease

F. Li, Ashutosh S. Phadte, Mayuri Bhatia, Sarah Barndt, Anthony R. Monte Carlo, Chun-Feng David Hou, Rong Yang, Stephen B. Strock, Anna Pluciennik

This study identifies how the Arg507His mutation in FAN1 impairs its interaction with PCNA and DNA cleavage, accelerating Huntington's disease onset.

Nature Communications · May 14, 2025Peer-reviewedBiochemistry