Dosage effect of multiple genes accounts for multisystem disorder of myotonic dystrophy type 1
Qi Yin, Hongye Wang, Na Li, Yifu Ding, Zhenfei Xie, Lifang Jin, Yan Li, Qiong Wang, Xinyi Liu, Liu‐Qing Xu, Qing Li, Yongjian Ma, Yanbo Cheng, Kai Wang, Cuiqing Zhong, , Jinsong Li
This study shows that reduced gene dosage in multiple genes causes multisystem disorders in DM1 by creating mouse models with multigene mutations.
Cell Research · Dec 18, 2019Peer-reviewedGenetics