Jiangang Song

This study shows that Olig1/2 knockout in gliogenesis shifts glial precursor cells to produce non-proliferative interneurons instead of oligodendrocyte precursors, and identifies dorsal cortical GPCs as origin of H3.3G34R/V-mutant tumors.

This study challenges the belief that lateral/caudal ganglionic eminence contributes significantly to cortical oligodendrocyte progenitor cells, showing instead that its contribution is minimal.