Chris Bizon

Every Cure Knowledge Graph: A Unified Biomedical Knowledge Graph for Drug Repurposing

The paper introduces EC-KG, a unified biomedical knowledge graph for drug repurposing that integrates multiple existing knowledge graphs to enhance coverage and uncover novel mechanistic pathways.

Dug: A Semantic Search Engine Leveraging Peer-Reviewed Knowledge to Span Biomedical Data Repositories

Dug is a semantic search tool that improves dataset retrieval across biomedical repositories by using curated knowledge graphs, outperforming Elasticsearch in recall and handling synonyms effectively.

Comparative analysis of functional assay evidence use by ClinGen Variant Curation Expert Panels

The paper evaluates how ClinGen Variant Curation Expert Panels (VCEPs) use functional assay evidence in variant classification, finding variability in assay selection and validation parameters.