MIP3α-RelMtb intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques
James T. Gordy, Jean J. Zheng, Amanda R. Maxwell, Rowan E. Bates, Alannah D. Taylor, Styliani Karanika, Heemee Ton, Jacob Meza, Yangchen Li, Jiaqi Zhang, Petros C. Karakousis, Richard B. Markham
This study shows that an intranasal DNA vaccine targeting RelMtb with MIP3α induces T-cell infiltration in the lungs of mice and macaques, enhancing immune responses against Mtb.
Vaccine · Jul 16, 2025Peer-reviewedImmunology