Developmental BiologyeLifePeer-reviewed
Inflammatory response in hematopoietic stem and progenitor cells triggered by activating SHP2 mutations evokes blood defects
Maja Šolman, Sasja Blokzijl-Franke, Florian Piques…·Jeroen den Hertog
This study identifies an inflammatory response in HSPCs with SHP2 mutations that drives MPN and suggests anti-inflammatory agents as potential therapies for JMML.
30 citations