Author

Leonie K. Amstein

Goethe University FrankfurtORCID 0000-0002-9524-0343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Ina KochiD· 3 shared Jennifer HannigiD· 3 shared Jörg AckermanniD· 3 shared Ivan ĐikićiD· 2 shared Alireza BeygiiD· 1 shared Börje Schweizer· 1 shared Christoph WelschiD· 1 shared Heiko GieseiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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3 shared papersSystems Biology

Ina KochORCID

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3 papers

Recent·Most cited

Systems BiologybioRxivPreprintApr 2, 2023

Stochastic modeling of the dynamics of Salmonella infection of epithelial cells

Jennifer Hannig, Alireza Beygi, Jörg Ackermann…·Ina Koch

This paper develops a stochastic model to simulate Salmonella infection dynamics in epithelial cells, predicting infection rates and bacterial load over time.

DOI 10.1101/2023.04.02.535247

humanstatistical model

𝕏 PostBluesky

Systems BiologybioRxivPreprintNov 2, 2021

Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways using Petri nets

Leonie K. Amstein, Jörg Ackermann, Jennifer Hannig…·Ina Koch

The paper constructs a Petri net model of TNFR1 signaling pathways to analyze cell survival, apoptosis, and necroptosis outcomes.

2 citations

statistical model

𝕏 PostBluesky

BioinformaticsBioinformaticsPeer-reviewedAug 8, 2018

isiKnock: in silico knockouts in biochemical pathways

Jennifer Hannig, Heiko Giese, Börje Schweizer…·Ina Koch

isiKnock predicts biological system behavior after knockouts using transition and Manatee invariants in biochemical pathway models.

8 citations

statistical modelsoftware / tool

𝕏 PostBluesky