Ina Koch

The paper identifies the transaminase-omega-amidase pathway as a redox-sensitive metabolic switch in endothelial glutamine metabolism, showing that NIT2 oxidation inhibits its activity and affects angiogenesis.

This paper develops a stochastic model to simulate Salmonella infection dynamics in epithelial cells, predicting infection rates and bacterial load over time.

This paper introduces a graph neural network approach for protein fold classification using protein topology graphs, achieving 82-100% accuracy on SCOPe and CATH datasets.

The paper constructs a Petri net model of TNFR1 signaling pathways to analyze cell survival, apoptosis, and necroptosis outcomes.

isiKnock predicts biological system behavior after knockouts using transition and Manatee invariants in biochemical pathway models.

The paper integrates genetic and transcriptome data to link neuropsychological traits to brain gene networks, identifying IQ-associated genetic variants in an autism cohort.

The paper quantifies spatial neighborhood preferences of cancer cells in Hodgkin lymphoma using whole slide images and statistical analysis.