Author

Aditi Madan

Fred Hutch Cancer CenterORCID 0000-0002-9537-451XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Akhila RajaniD· 3 shared Ava E. BrentiD· 2 shared Kevin KellyiD· 2 shared Shannon MarschalliD· 2 shared Sunidhi RanganathaniD· 2 shared Camille E Sullivan· 1 shared Jordan J. Wong· 1 shared Julien DubrulleiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenomics

Akhila RajanORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Atg8 orchestrates stress-responsive chromatin programs across immunity and metabolism

Kevin Kelly, Navyashree A Ramesh, Sunidhi Ranganathan, Aditi Madan, Shannon Marschall, Robert L. Unckless, Akhila Rajan

This study identifies Atg8/LC3 as a stress-responsive chromatin cofactor that coordinates immune and metabolic transcription through interactions with NF-κB/Dif in Drosophila.

bioRxiv · May 28, 2026 · PreprintGenomics

Adipocyte metabolic state regulates glial phagocytic function

Mroj Alassaf, Aditi Madan, Sunidhi Ranganathan, Shannon Marschall, Jordan J. Wong, Zachary H Goldberg, Ava E. Brent, Akhila Rajan

This study shows that adipocyte metabolic changes due to an obesogenic diet affect glial phagocytic function in Drosophila brains by altering lipid signaling and receptor expression.

Cell Reports · May 1, 2025Peer-reviewedNeuroscience

NUCLEAR RETENTION OF LEPTIN/UPD2 REGULATES ORGANISMAL RESILIENCE TO NUTRIENT EXTREMES

Michelle E Poling, Camille E Sullivan, Aditi Madan, Kevin Kelly, Ava E. Brent, Julien Dubrulle, Prashant Raghavan, Akhila Rajan

The paper shows that Atg8 regulates Upd2 nuclear retention during starvation, enhancing starvation resilience and innate immunity in Drosophila.

bioRxiv · Jan 29, 2021 · PreprintMolecular Biology