Razvan Costin Stan

Fever temperatures modulate intraprotein dynamics and enhance the binding affinity between monoclonal antibodies and the Spike protein from SARS-CoV-2

The paper investigates how mild fever temperatures affect the binding affinity of antibodies to the SARS-CoV-2 Spike protein using molecular dynamics simulations.

Whole-Genome Sequences of the Severe Acute Respiratory Syndrome Coronavirus-2 obtained from Romanian patients between March and June of 2020

The paper reports whole-genome sequences of SARS-CoV-2 from Romanian patients and analyzes mutations in the Spike glycoprotein's impact on protein stability and infectivity.

Higher levels of grp78 and lower levels of tlr4 anticipate a positive evolution of sepsis and patient survival

The paper correlates grp78 and tlr4 mRNA levels in septic patients to predict sepsis progression and survival.

Molecular memory of periodic thermal stimulation in an immune complex

The paper shows that periodic thermal stimulation of immune complex partners leads to memory of the stimulus in their binding affinity characteristics.