Stable and assayable polymicrobial human airway model reveals complex interactions between Pseudomonas aeruginosa and lung commensals
Sarah M. Spencer, Karla N. Valenzuela‐Valderas, Brendan M. Leung
The paper develops an ATPS-based co-culture model to study polymicrobial interactions in the human airway, showing Pseudomonas aeruginosa disrupts epithelial barriers while commensals mitigate this effect.
bioRxiv · Oct 30, 2025 · PreprintMicrobiology