Author

Sarah M. Spencer

Dalhousie University

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Microbiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brendan M. LeungiD· 1 shared Karla N. Valenzuela‐ValderasiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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1 shared paperMicrobiology

Brendan M. LeungORCID

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1 paper

Recent·Most cited

MicrobiologybioRxivPreprintOct 30, 2025

Stable and assayable polymicrobial human airway model reveals complex interactions between Pseudomonas aeruginosa and lung commensals

Sarah M. Spencer, Karla N. Valenzuela‐Valderas, Brendan M. Leung

The paper develops an ATPS-based co-culture model to study polymicrobial interactions in the human airway, showing Pseudomonas aeruginosa disrupts epithelial barriers while commensals mitigate this effect.

DOI 10.1101/2025.10.30.685207

humanbulk RNA-seq

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