The chromatin, topological and regulatory properties of pluripotency-associated poised enhancers are conserved in vivo
Giuliano Crispatzu, Rizwan Rehimi, Tomás Pachano, Tore Bleckwehl, Sara Cruz-Molina, Cally Xiao, Esther Mahabir, Hisham Bazzi, Álvaro Rada-Iglesias
The paper shows that poised enhancers' chromatin and 3D features are conserved in vivo in mouse and chicken embryos, and they play essential roles in developmental gene induction.
Nature Communications · Jul 16, 2021Peer-reviewedMolecular Biology