ADAPTATION AGAINST LONG-TERM PROTEIN DEPRIVATION TRADES OFF WITH IMMUNOCOMPETENCE AND THE ABILITY TO SURVIVE PATHOGENIC INFECTIONS
Saubhik Sarkar, Dipendra Nath Basu, Simran Sethi, Bodhisatta Nandy, Imroze Khan
This study shows that Drosophila melanogaster selected for increased early-life reproduction under protein limitation show reduced immune resistance and survival after infection, with these effects being sex-specific and mitigated by mating.
bioRxiv · Sep 10, 2025 · PreprintEvolutionary Biology