Developmental BiologyJournal of the American Society of NephrologyPeer-reviewed
Nephron progenitor maintenance is controlled through FGFs and Sprouty1 Interaction
Sung‐Ho Huh, Ligyeom Ha, Hee‐Seong Jang
This study identifies Sprouty1's role in regulating FGF signaling to maintain nephron progenitors, showing that Spry1 haploinsufficiency rescues renal agenesis and progenitor depletion caused by Fgf9/Fgf20 loss.
22 citations