Sung‐Ho Huh

Mechanism of Renal Cyst Initiation and Progression Through ETV Transcription Factors and Hedgehog Signaling

This study identifies distinct genetic and molecular mechanisms regulating renal cyst initiation and progression using ETV transcription factors and hedgehog signaling inhibition.

Mesenchymal ETV Transcription Factors Regulate Cochlear Length

The paper identifies ETV4 and ETV5 as downstream regulators of mesenchymal FGF signaling that promote cochlear lengthening during development.

Nephron progenitor maintenance is controlled through FGFs and Sprouty1 Interaction

This study identifies Sprouty1's role in regulating FGF signaling to maintain nephron progenitors, showing that Spry1 haploinsufficiency rescues renal agenesis and progenitor depletion caused by Fgf9/Fgf20 loss.

Tumor-free elongation of mammalian nephrogenesis by excess fetal GDNF

This study shows that excess fetal GDNF can prolong nephrogenesis in postnatal mouse kidneys without increasing tumor risk.

Sox2 and FGF20 interact to regulate organ of Corti hair cell and supporting cell development in a spatially-graded manner

This paper investigates the interaction between Sox2 and Fgf20 in regulating organ of Corti development, showing their spatially-graded roles in specification and differentiation.