Author

Federica Benigni

Bambino Gesù Children's HospitalORCID 0000-0002-9635-3948Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Amélie BarthelemyiD· 1 shared Chiara MarioliiD· 1 shared Claudia CompagnucciiD· 1 shared Frank W. PfriegeriD· 1 shared Marco TartagliaiD· 1 shared Martina ParenteiD· 1 shared Nicolò CicolaniiD· 1 shared Rossella BorghiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Amélie BarthelemyORCID

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Author profile →

1 paper

Recent·Most cited

Pharmacological BET Protein Inhibition Reverts Niemann-Pick Type C Disease-Associated Changes in Human iPSC-Derived Cortical Neurons

Federica Benigni, Martina Parente, Chiara Marioli, Rossella Borghi, Nicolò Cicolani, Amélie Barthelemy, Stefania Petrini, Marco Tartaglia, Frank W. Pfrieger, Valentina Pallottini, Claudia Compagnucci

This study uses iPSC-derived neurons from NPC1 patients to show that BET inhibition with JQ1 improves neuronal viability and reduces cholesterol accumulation.

bioRxiv · Sep 3, 2026 · PreprintNeuroscience