Author

Wenyuan Han

Huazhong Agricultural UniversityORCID 0000-0002-9636-6415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Approach:experimental assay· 1

Frequent Co-Authors

Qunxin SheiD· 2 shared Rafael Pinilla‐RedondoiD· 2 shared Chen yu· 1 shared Donghai PengiD· 1 shared Fan ruipeng· 1 shared Han zhenhao· 1 shared Hao FengiD· 1 shared Huan HeiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Qunxin SheORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintDec 8, 2025

Leveraging defense system modularity to discover anti-phage systems

Liu yanqiu, Tan keyi, Han zhenhao…·Wenyuan Han

The paper identifies new anti-phage defense systems in E. coli by analyzing modular defensive domains, validating several candidates with anti-phage activity.

DOI 10.64898/2025.12.08.692795

E. coliproteomics

𝕏 PostBluesky

MicrobiologySciencePeer-reviewedFeb 20, 2025

Base-modified nucleotides mediate immune signaling in bacteria

Zhifeng Zeng, Zeyu Hu, Ruiliang Zhao…·Wenyuan Han

The paper identifies a bacterial anti-phage system that uses nucleobase modification to generate immune messengers, leading to population-level defense through infected cell death.

40 citationstop 1%

bacteria (other)experimental assay

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BioinformaticsRNA BiologyPeer-reviewedJun 18, 2018

Conserved accessory proteins encoded with archaeal and bacterial Type III CRISPR-Cas gene cassettes that may specifically modulate, complement or extend interference activity

Shiraz Ali Shah, Omer S. Alkhnbashi, Juliane Behler…·Rolf Backofen

The paper identifies 39 new Type III CRISPR-Cas associated gene families using comparative genomics and presents them in an online database.

92 citationstop 4%

statistical modeldatabase / resource

𝕏 PostBluesky