Qunxin She

The paper identifies BaCas12a3 as a new type V CRISPR effector that inhibits growth through tRNA cleavage without causing DNA damage.

This study identifies Sul14a as a nucleoid-associated protein in Sulfolobales that regulates chromatin organization and cell cycle progression through DNA binding and transcriptional changes.

This study identifies three transcription factors that regulate the archaeal cell cycle in Saccharolobus islandicus through a braking point mechanism, differing from eukaryotic regulation.

This study shows that phosphorylation of a proteasome subunit by ePK2 inhibits proteasome assembly and regulates cell division in Sulfolobales archaea.

This study identifies a new class of OLD family ATPases in archaea, showing Cran1 is essential for cell cycle progression rather than antiviral defense.

The paper identifies a bacterial anti-phage system that uses nucleobase modification to generate immune messengers, leading to population-level defense through infected cell death.

This study characterizes a type III CRISPR-Cas system, revealing how RNA binding allosterically activates and suppresses Cas10 DNase activity through specific 3' anti-tag interactions.

The paper identifies 39 new Type III CRISPR-Cas associated gene families using comparative genomics and presents them in an online database.