José María Huerta

This paper develops a multi-cancer PRS constellation model integrating genetic and lifestyle factors to predict cancer risk, finding that lifestyle PRSs have limited utility but genetic PRSs remain important.

The paper introduces a pipeline to normalize and pool metabolomics data across studies, improving comparability and reducing inter-study variability.

This study uses Mendelian randomization to show that higher physical activity levels are associated with lower risks of breast and colorectal cancer.