BioinformaticsBMC GenomicsPeer-reviewed
METHimpute: Imputation-guided construction of complete methylomes from WGBS data
Aaron Taudt, David Roquis, Amaryllis Vidalis…·Maria Colomé‐Tatché
METHimpute constructs complete methylomes from low-coverage WGBS data using a Hidden Markov Model, achieving high accuracy at 6X coverage compared to 60X.