Author

David Roquis

Centre National de la Recherche ScientifiqueORCID 0000-0001-5265-3132Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:imputation· 1 Assay:metagenomics· 1 Organism:non-human primate· 1

Frequent Co-Authors

Aaron TaudtiD· 1 shared Amaryllis VidalisiD· 1 shared Ariadna Picart-PicoloiD· 1 shared Céline CosseauiD· 1 shared Christoph GrunauiD· 1 shared Christophe DebonnevilleiD· 1 shared Franco FaoroiD· 1 shared Frank M. JohannesiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioinformatics

Aaron TaudtORCID

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3 papers

Recent·Most cited

MicrobiologymSystemsPeer-reviewedApr 9, 2025

From insect endosymbiont to phloem colonizer: comparative genomics unveils the lifestyle transition of phytopathogenic Arsenophonus strains

Mathieu Mahillon, Christophe Debonneville, Raphaël Groux…·Jessica Dittmer

This paper investigates the genetic mechanisms of lifestyle transition in two phytopathogenic Arsenophonus strains, identifying shared orthologs and horizontal gene transfer events involved in phloem colonization.

10 citations

metagenomicsstatistical model

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Molecular BiologybioRxivPreprintAug 1, 2019

The tropical coral Pocillopora acuta has a mosaic DNA methylome, an unusual chromatin structure and shows histone H3 clipping

David Roquis, Ariadna Picart-Picolo, Kelly Brener-Raffalli…·Jérémie Vidal‐Dupiol

This paper describes a method to purify coral chromatin, reports the first methylome of Pocillopora acuta with a mosaic methylation pattern, and identifies an unusual chromatin structure and histone H3 clipping.

2 citations

non-human primateDNA methylation

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BioinformaticsBMC GenomicsPeer-reviewedJun 7, 2018

METHimpute: Imputation-guided construction of complete methylomes from WGBS data

Aaron Taudt, David Roquis, Amaryllis Vidalis…·Maria Colomé‐Tatché

METHimpute constructs complete methylomes from low-coverage WGBS data using a Hidden Markov Model, achieving high accuracy at 6X coverage compared to 60X.

51 citations

plant (other)whole-genome sequencing

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