Author

Christoph Stange

German Cancer Research CenterORCID 0000-0002-9663-3472Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Amirhossein SakhtemaniD· 2 shared Annika SchneideriD· 2 shared Bernhard KüsteriD· 2 shared Cecilia Bang JenseniD· 2 shared Daniel HübschmanniD· 2 shared Firas HamoodiD· 2 shared Florian P BayeriD· 2 shared Jennifer HüelleiniD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Amirhossein SakhtemanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Catabolism of extracellular glutathione is a driver of metastasis formation

Felix C. E. Vogel, Florian Roehrig, Danny Schilling, Adriano B Chaves-Filho, Greta Mattavelli, Maximilian Kraemer, Julie Haenlin, Alina M. Winkelkotte, Valentine Fournier, Kamal M. Al-Shami, H. Rohdjeß, Philipp Poeller, Tanja Poth, Christoph Stange, Bernhard Kuester, , Almut Schulze

The paper identifies extracellular glutathione catabolism as a driver of metastasis by enabling proliferation and oxidative stress resistance in metabolically challenging microenvironments.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology

TOPAS: phosphoproteome data analysis and decision support platform for molecular tumor boards

Cecilia Bang Jensen, Amirhossein Sakhteman, Firas Hamood, Annika Schneider, Julia Wortmann, Maria‐Veronica Teleanu, Peter Horak, Florian P Bayer, Christoph Stange, Jennifer Hüellein, Daniel Hübschmann, Anton George Henssen, Stefan Fröhling, Bernhard Küster, Matthew The

TOPAS converts phosphoproteomic data into patient-specific reports for molecular tumor boards, focusing on clinically relevant signaling and therapeutic targets.

bioRxiv · Jul 13, 2026 · PreprintBioinformatics

Prospective pan-cancer phosphoproteomics at clinical scale extends therapeutic options in precision oncology

Annika Schneider, Julia Wortmann, Cecilia Bang Jensen, Leonardo Estrada Duenas, Maria‐Veronica Teleanu, Amirhossein Sakhteman, Firas Hamood, Florian P Bayer, Christoph Stange, Jeremiah Bintang Santoso, Jennifer Hüellein, Nindo B. Punturi, Lee Dolat, Peter Horak, Resch Moritz, , Bernhard Küster

This study uses pan-cancer phosphoproteomics to identify therapeutic targets and improve precision oncology by analyzing 1,998 tumor samples and developing new scores for kinase activity and immune response.

bioRxiv · Jul 9, 2026 · PreprintCancer Biology