Author

Anke R.M. Kraft

Medizinische Hochschule HannoverORCID 0000-0002-9666-0753Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:deconvolution· 1 Assay:DNA methylation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Markus CornbergiD· 3 shared Benjamin MaasoumyiD· 2 shared Heiner H. WedemeyeriD· 2 shared Alexander DietrichiD· 1 shared Ayesha Lietzau· 1 shared Birgit BremeriD· 1 shared Carlos OltmannsiD· 1 shared Cheng‐Jian XuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Markus CornbergORCID

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3 papers

Recent·Most cited

Non-selective beta blockers reduce bystander CD8+ T cell activation in decompensated liver cirrhosis

Ayesha Lietzau, Ines Tapken, Soyoung Kim, Roni Souleiman, Erich Freyer, Anke R.M. Kraft, Sarah Schütte, Tammo Lambert Tergast, Benjamin Maasoumy, Heiner H. Wedemeyer, Isabell Drath, Gabriele Zurek, Eui‐Cheol Shin, Markus Cornberg, Christian Niehaus

This study shows that non-selective beta blockers reduce bystander CD8+ T cell activation in decompensated liver cirrhosis without affecting antigen-specific responses.

bioRxiv · Nov 18, 2025 · PreprintImmunology

Unifying DNA methylation-based in silico cell-type deconvolution with deconvMe

Alexander Dietrich, Lina-Liv Willruth, Korbinian Pürckhauer, Carlos Oltmanns, Moana Witte, Sebastian Klein, Anke R.M. Kraft, Markus Cornberg, Markus List

The paper introduces deconvMe, an R package for DNA methylation-based cell-type deconvolution, and compares its results to gene expression and experimental data.

Bioinformatics Advances · Dec 26, 2024Peer-reviewedBioinformatics

Enhancing HBV-specific T cell responses through a combination of epigenetic modulation and immune checkpoint inhibition

Melanie Urbanek‐Quaing, Yin-Han Chou, Manoj Kumar Gupta, Katja Steppich, Birgit Bremer, Hagen Schmaus, Katja Deterding, Benjamin Maasoumy, Heiner H. Wedemeyer, Cheng‐Jian Xu, Anke R. M. Kraft, Markus Cornberg

This study shows that combining decitabine with PD-L1 enhances HBV-specific T cell responses in vitro by reversing epigenetic imprints and improving IFN-gamma levels.

Hepatology · Dec 19, 2024Peer-reviewedImmunology