Author

Iris A. Speigel

Weill Cornell MedicineORCID 0000-0002-9679-0566Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:electronic health records· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Hugh C. HemmingsiD· 2 shared Kishan Patel· 1 shared Vanessa Osman· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersNeuroscience

Hugh C. HemmingsORCID

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2 papers

Recent·Most cited

Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons

Iris A. Speigel, Kishan Patel, Vanessa Osman, Hugh C. Hemmings

This study shows volatile anesthetics inhibit presynaptic cGMP signaling and reduce excitability in rat hippocampal neurons by affecting Ca2+ influx and neurotransmitter release.

Neuropharmacology · Sep 6, 2023Peer-reviewedNeuroscience

Differential inhibition of GABA release from mouse hippocampal interneuron subtypesby the volatile anesthetic isoflurane

Iris A. Speigel, Hugh C. Hemmings

This study investigates how isoflurane affects synaptic vesicle exocytosis in different hippocampal interneuron subtypes, finding subtype-specific inhibition linked to voltage-gated sodium channel expression.

bioRxiv · Oct 1, 2020 · PreprintNeuroscience