A Complex Evolutionary History for the Disease Susceptibility CDHR3 Locus
Mary B. O’Neill, Guillaume Laval, João C. Teixeira, Ann C. Palmenberg, Caitlin S. Pepperell
The paper investigates the evolutionary history of the CDHR3 locus, finding that the protective variant against RV-C and asthma has been subject to selection in recent human evolution, though not as a classical selective sweep.
Human Molecular Genetics · Dec 10, 2019Peer-reviewedGenetics