João C. Teixeira

This study analyzes 68 ancient Portuguese genomes over 5,000 years, revealing migration patterns and genetic continuity, with influences from local, African, and Mediterranean populations.

This study benchmarks GLIMPSE imputation on low coverage genomes from underrepresented populations, showing improved performance when using target population genetic information.

This study uses genome data to show that most Papuan-related ancestry in Wallacea comes from New Guinea migrations, not from ancient human settlers.

This study evaluates the effectiveness of the Twist Ancient DNA reagent for enriching ancient human SNPs, finding it robust for up to 27% endogenous DNA content with two rounds of enrichment.

The paper shows that admixture in modern European genomes has masked over 50 historic hard sweeps, suggesting underappreciation of historical selection in human evolution.

The paper investigates the evolutionary history of the CDHR3 locus, finding that the protective variant against RV-C and asthma has been subject to selection in recent human evolution, though not as a classical selective sweep.

The paper introduces NCD2, a statistic to detect long-term balancing selection in human genomes, finding it affects 0.6% of genomic windows and 0.8% of positions, with many novel targets.