Author

Caitlin S. Pepperell

University of Wisconsin–MadisonORCID 0000-0002-6324-1333Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Approach:statistical model· 1

Frequent Co-Authors

Ann C. PalmenbergiD· 1 shared Guillaume LavaliD· 1 shared Holly J. MurrayiD· 1 shared João C. TeixeiraiD· 1 shared John F. KernieniD· 1 shared Kadee N. LawrenceiD· 1 shared Madison A. YoungblomiD· 1 shared Mary B. O’NeilliD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Ann C. PalmenbergORCID

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2 papers

Recent·Most cited

Contingencies in biofilm adaptation of Mycobacterium tuberculosis

John F. Kernien, Madison A. Youngblom, Tracy M. Smith, Sydney S Fry, Mohamed A Mohamed, Holly J. Murray, Kadee N. Lawrence, Caitlin S. Pepperell

This study evolves Mycobacterium tuberculosis biofilms to examine adaptation mechanisms, finding that genetic variation and mutational biases influence replicability and that some biofilm-associated mutations are common in natural TB infections.

bioRxiv · Jun 7, 2024 · PreprintEvolutionary Biology

A Complex Evolutionary History for the Disease Susceptibility CDHR3 Locus

Mary B. O’Neill, Guillaume Laval, João C. Teixeira, Ann C. Palmenberg, Caitlin S. Pepperell

The paper investigates the evolutionary history of the CDHR3 locus, finding that the protective variant against RV-C and asthma has been subject to selection in recent human evolution, though not as a classical selective sweep.

Human Molecular Genetics · Dec 10, 2019Peer-reviewedGenetics