Restricting Dietary Isoleucine Promotes Foxo3-Dependent Mitochondrial Respiration by Reducing Caloric Intake
Julianne Austin, Minzhen He, Zhi Yang, Dayyan Sayed, Danish H Sayed, Maha Abdellatif
This study shows that restricting dietary isoleucine improves cardiac health by enhancing Foxo3 expression and mitochondrial function through reduced caloric intake.
bioRxiv · Jul 1, 2026 · PreprintMolecular Biology