Maha Abdellatif

The paper shows that restoring Klf9 expression during cardiac hypertrophy initially inhibits hypertrophy but leads to early-onset heart failure.

This study shows that restricting dietary isoleucine improves cardiac health by enhancing Foxo3 expression and mitochondrial function through reduced caloric intake.

This study shows that constant Klf9 expression in cardiomyocytes causes metabolic issues and heart failure by disrupting transcriptional and metabolic balance.

The paper identifies H2A.Z-dependent and -independent recruitment of metabolic enzymes to chromatin and shows their role in histone modifications in mouse heart cells.