Author

Clifford Lawrence Librach

University of TorontoORCID 0000-0002-9699-4059Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Svetlana MadjunkovaiD· 2 shared Amanda J MacFarlaneiD· 1 shared Brandon A. WyseiD· 1 shared Christine LafleuriD· 1 shared Daniel AriadiD· 1 shared Donovan ChaniD· 1 shared Gelareh Motamedi· 1 shared Guillaume BourqueiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersGenomics

Svetlana MadjunkovaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Altered sperm DNA methylation in overweight men associates with transposable element regulation of paternal origins of risk in children

Mathieu Schulz, Xiaojian Shao, Romain Lambrot, Christine Lafleur, Donovan Chan, Marie-Charlotte Dumargne, Amanda J MacFarlane, Sergey I. Moskovtsev, Guillaume Bourque, Tomi Pastinen, Clifford Lawrence Librach, Hope Alberta Weiler, Jacquetta M. Trasler, Sarah Kimmins

The paper identifies altered sperm DNA methylation in overweight men linked to transposable element regulation and potential impacts on offspring neurodevelopmental risks.

bioRxiv · Sep 15, 2025 · PreprintDevelopmental Biology

Aberrant landscapes of maternal meiotic crossovers contribute to aneuploidies in human embryos

Daniel Ariad, Svetlana Madjunkova, Mitko Madjunkov, Siwei Chen, Rina Abramov, Clifford Lawrence Librach, Rajiv C. McCoy

The paper infers sex-specific meiotic recombination landscapes from low-coverage embryo sequencing data, revealing chromosome-specific patterns linked to aneuploidies.

Genome Research · Jan 1, 2024Peer-reviewedGenomics

Towards Improving Embryo Selection: Simultaneous Next Generation Sequencing Of DNA And RNA From A Single Trophectoderm Biopsy

Noga Fuchs Weizman, Brandon A. Wyse, Ran Antes, Zenon Ibarrientos, Mugundhine Sangaralingam, Gelareh Motamedi, Valeriy Kuznyetsov, Svetlana Madjunkova, Clifford Lawrence Librach

This paper develops a method to simultaneously analyze genomic and transcriptomic data from a single embryo biopsy to improve embryo selection in fertility treatments.

Scientific Reports · Feb 27, 2019Peer-reviewedDevelopmental Biology