Marta Badia

This study quantifies how mutations affect IAPP amyloid formation using deep mutational scanning and identifies key residues involved in aggregation.

The paper identifies a conserved gene expression signature linked to proliferation rate, showing it predicts growth rates across species and reveals lineage-specific differences in proliferation dynamics.

The paper quantifies the effects of mutations on amyloid beta fibril nucleation using deep mutational scanning and identifies key residues that prevent nucleation, validating a cell-based assay for familial Alzheimer's disease mutations.