The Interferon γ Pathway Enhances Pluripotency and X-Chromosome Reactivation in iPSC Reprogramming
Mercedes Barrero, Anna V. López-Rubio, Aleksey Lazarenkov…·Bernhard Payer
This study identifies the IFNγ pathway's role in accelerating iPSC reprogramming and X-chromosome reactivation through STAT3 signaling and TET-mediated demethylation.