Bogdan Andrei Mirauta

The paper analyzes the gut microbiome and resistome in a Romanian cohort with high antibiotic use, identifying microbiome features, antimicrobial resistance patterns, and immune-related associations.

The paper maps regulatory effects of human disease variants in pluripotent cells, identifying cis- and trans-QTL across 18,556 genes and linking them to GWAS traits.

The paper characterizes proteome variation across 202 human iPSC lines, identifies 700 pQTLs, and links pQTLs to disease-associated GWAS variants.

The paper examines how structural variants and short tandem repeats affect gene expression and complex traits, identifying high-impact variants associated with multiple genes and GWAS traits.

The paper discovers and genotypes a comprehensive set of structural variants and short tandem repeats using multiple algorithms and replicates, creating a well-characterized map of these variants.

The paper shows that erosion of X chromosome inactivation in human iPSCs leads to increased protein expression from X-linked and autosomal genes, altering protein-RNA correlations and increasing protein content.

The paper characterizes interaction-mediated control of protein abundance using multi-omics data from cancer samples and finds that 42% of proteins show post-transcriptional regulation.