Qiang Gao

SCALE: Scalable Conditional Atlas-Level Endpoint transport for virtual cell perturbation prediction

A set-aware latent transport model predicts treated cell populations from unpaired controls, keeps perturbation-specific signal in CRISPR, drug and cytokine data, and guided a cytokine choice tested in three donors.

OriGene: A Self-Evolving Virtual Disease Biologist Automating Therapeutic Target Discovery

OriGene identifies therapeutic targets by integrating diverse data modalities and outperforms human experts and models in accuracy and robustness.