Author

Lindsey A. George

Children's Hospital of PhiladelphiaORCID 0000-0002-9763-1559Unclaimed ORCID profile · follow to get notified of new preprints

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

Anna R. SternbergiD· 1 shared Cristina Martos-RusiD· 1 shared Robert J. Davidson· 1 shared Xueyuan LiuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anna R. SternbergORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyNature CommunicationsPeer-reviewedAug 21, 2024

Overcoming Hemophilia A Gene Therapy Limitations with an Enhanced Function Factor VIII Variant

Anna R. Sternberg, Cristina Martos-Rus, Robert J. Davidson…·Lindsey A. George

This study shows an enhanced FVIII variant (FVIII-QQ) can normalize hemostasis at low expression levels in hemophilia A mice, potentially improving gene therapy durability and safety.

23 citationstop 2%

mouseprotein sequence

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