Schlafen-11 and -9 are innate immune sensors for intracellular single-stranded DNA
Peng Zhang, Xiaoqing Hu, Zekun Li, Qian Liu, Lele Liu, Ying-Ying Jin, Sizhe Liu, Xiang Zhao, Jianqiao Wang, De‐Long Hao, Hou‐Zao Chen, De‐Pei Liu
The paper identifies Schlafen-11 and -9 as innate immune sensors that recognize intracellular single-stranded DNA containing CGT motifs, leading to cytokine expression and cell death.
Science Immunology · Jun 14, 2024Peer-reviewedImmunology