Author

Xiang Zhao

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 1 Evolutionary Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alexander PutraiD· 1 shared Angel AngeloviD· 1 shared Cao Deng· 1 shared Chenchen Xu· 1 shared Daniela I. Drautz‐MosesiD· 1 shared Danyu Chen· 1 shared Delong Hao· 1 shared Depei Liu· 1 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperGenomics

Alexander PutraORCID

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Author profile →

4 papers

Recent·Most cited

Structure-aware protein function prediction at isoform resolution

Felicia Jiang, Runhao Zhao, Feng Liang, Xiang Zhao, Taoyong Cui, Zhenchao Tang, Y S Zhang, Danyu Chen, minghao Xu, Yi Shuai, Tianli Luo, Xiangeng Wang, Chenchen Xu, Ziwei Wang, Weixin Zeng, , Xin Wang

This study develops a framework for predicting protein function and domain annotation at isoform resolution using structural and sequence data, showing strong performance in benchmark tests and capturing domain changes across isoforms.

bioRxiv · Jun 7, 2026 · PreprintCancer Biology

Near completely reversing the γ- to β-globin switch by enhancer release, retargeting and reinforcing

Nanyu Wang, Ke Yang, Xuemin Xie, Shenshen Cui, Xiaoya Pei, Xiang Zhao, Delong Hao, Yuyan Jia, Gaohui Yang, Rongrong Liu, Ping Chen, Wenji Dong, Yue Huang, Xiang Lv, Zhuqin Zhang, Depei Liu

This study demonstrates that combined editing of CACCC and TGACCA motifs can nearly reverse the γ- to β-globin switch by redirecting enhancer-promoter interactions.

bioRxiv · Feb 1, 2026 · PreprintMolecular Biology

COMPARATIVE METAGENOMIC ASSESSMENT OF SHORT- AND LONG-READ SEQUENCING TECHNOLOGIES REVEALS UNKNOWN MICROBIAL INFORMATION IN A COMPLEX ENVIRONMENTAL SAMPLE

Rubén Díaz‐Rúa, Daniela I. Drautz‐Moses, Xiang Zhao, Sadhasivam Perumal, Luke E. Esau, Angel Angelov, Alexander Putra, Patrick Driguez, Ming Sin Cheung, Emanuele Palescandolo

The paper compares short- and long-read sequencing technologies in metagenomics, showing that longer short reads with optimal prep improve assembly and protein detection without needing more sequencing depth.

bioRxiv · Dec 26, 2025 · PreprintGenomics

Comparative genomics and metagenomics analyses of endangered Père David’s deer (Elaphurus davidianus) provide insights into population recovery

Xuejing Zhang, Cao Deng, Jingjing Ding, Yi Ren, Xiang Zhao, Shishang Qin, Shilin Zhu, Zhiwen Wang, Xiaoqiang Chai, Huasheng Huang, Yuhua Ding, Guoqing Lu, Lifeng Zhu

This study uses genomics and metagenomics to analyze the population recovery of Père David’s deer, identifying genetic and microbial factors contributing to their resilience.

bioRxiv · Sep 5, 2016 · PreprintEvolutionary Biology