Liam Michael Grover

Elevated hydrostatic pressure modulates endothelial junctional mechanotransduction through VE-cadherin remodelling and altered association with YAP1, EPS8: an endothelium-on-chip study

This study investigates how elevated hydrostatic pressure affects endothelial junctions using an endothelium-on-chip model, revealing changes in VE-cadherin structure, YAP1 localization, and EPS8 interactions.

Engineering an in vitro spinal column: Manufacturing designs and emerging solutions for producing an axial mechanobiological system

This paper develops a biomimetic spinal model to study axial mechanobiology and multi-segment coupling, enabling time-dependent adaptations and tissue maturation in vitro.

Elevated hydrostatic pressure acts via piezo-1 to destabilise VE-cadherin junctions: an endothelium-on-chip study

This study shows elevated hydrostatic pressure affects VE-cadherin junctions via piezo-1, with effects dependent on shear stress duration and intensity.