Potent neutralization of Marburg virus by a vaccine-elicited monoclonal antibody
Amin Addetia, Lisa Perruzza, Young‐Jun Park, Matthew McCallum, Cameron Stewart, Jack T Brown, Alessia Donati, Katja Culap, Alessio Balmelli, Michal Gaži, Ricardo Carrion, Davide Corti, Fabio Benigni, David Veesler
This study identifies a potent monoclonal antibody, MARV16, that broadly neutralizes Marburg virus and related viruses, with a cryo-EM structure revealing its mechanism of action.
bioRxiv · May 14, 2025 · PreprintImmunology