CCR5/CCL5 Links Mitochondrial Dysfunction to Angiotensin II Vascular Injury
Gustavo Félix Pimenta, Ariane Bruder‐Nascimento, Tyler Beling, Sergio Guerrero, Luis Oliveira de Moraes, Carlos Renato Tirapelli, Thiago B Bruder-Nascimento
This study shows that Ang II enhances CCL5/CCR5 signaling, leading to mitochondrial dysfunction and oxidative stress in vascular smooth muscle cells, contributing to vascular injury in hypertension.
bioRxiv · Jul 22, 2026 · PreprintPhysiology