Apical restriction of the planar cell polarity component VANGL in pancreatic ducts is required to maintain epithelial integrity
Lydie C. Flasse, Siham Yennek, Cédric Cortijo, Irene Seijo-Barandiarán, Marine R.-C. Kraus, Anne Grapin‐Botton
The paper shows that apical restriction of VANGL in pancreatic ducts is essential for epithelial integrity, with loss of restriction causing cell death and extrusion.
Cell Reports · May 1, 2020Peer-reviewedDevelopmental Biology