BiochemistrybioRxivPreprint
Loss of α2,3-linked sialoside in the receptor-binding site of a H5N1 influenza hemagglutinin identified in a human patient
John H. Ni, Saeid Malek Zadeh, Alison Berezuk…·Sriram Subramaniam
The paper identifies a H5N1 influenza strain with reduced sialic acid binding due to loss of α2,3-linked sialoside in its HA receptor-binding site, correlating with lower virulence despite severe disease.
DOI 10.64898/2026.01.19.700419