Selective Enhancement of the Interneuron Network and Gamma-Band Power via GluN2C/GluN2D NMDA Receptor Potentiation
Chad R. Camp, Tue G. Banke, Hao Xing, Kuai Yu, Riley E. Perszyk, Matthew P. Epplin, Nicholas S. Akins, Jing Zhang, Tim A. Benke, Hongjie Yuan, Dennis C. Liotta, Stephen F. Traynelis
This paper describes a GluN2C/GluN2D-selective NMDA receptor modulator that enhances inhibitory interneuron activity and gamma-band power, with potential therapeutic applications for neuropsychiatric disorders.
The Journal of Physiology · Jun 25, 2025Peer-reviewedNeuroscience