GeneticsGenetic EpidemiologyPeer-reviewed
GxE PRS: Genotype-environment interaction in polygenic risk score models for quantitative and binary traits
Dovini Jayasinghe, Md. Moksedul Momin, Kerri Beckmann…·Sang Lee
This study introduces a novel GxE PRS model that improves type 1 error control and statistical power for genetic risk prediction, with applications to quantitative and binary traits.
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