Beben Benyamin

This study identifies genetic factors underlying personality meta-traits stability and plasticity and their links to psychopathology using GWAS and structural equation modeling.

This study identifies 10 novel genomic loci associated with intrinsic capacity using GWAS on UK Biobank and CLSA data, revealing genetic correlations with cellular processes and traits related to healthy aging.

This study examines cross-ancestry genetic architecture of cholesterol traits, finding significant genetic heterogeneity and identifying concordant SNPs with higher predictive ability.

This study introduces a novel GxE PRS model that improves type 1 error control and statistical power for genetic risk prediction, with applications to quantitative and binary traits.

This paper introduces a method to estimate cross-ancestry genetic correlation using individual-level data, finding significant genetic heterogeneity in obesity between African and European ancestry groups.

A genome-wide association study of 69,369 schizophrenia cases and 236,642 controls identifies 270 risk loci, prioritizes 130 genes, and links common and rare risk variants to neuronal synaptic biology.

The paper identifies genetic-by-environment interactions affecting diabetes-related metabolic traits using UK Biobank data, showing lifestyle impacts vary by genetic background.

This study performs a GWAS on random glucose measurements in 493,036 individuals, identifying 128 loci associated with glycaemic traits and providing insights into diabetes biology and treatment.

This study identifies schizophrenia genetic associations in East Asian and European populations, finding similar genetic effects across ancestries but highlighting challenges in polygenic risk prediction across groups.