Cell BiologybioRxivPreprint
JAK and MEK Pathways as Therapeutic Targets for Saphenous Vein Smooth Muscle Cell Dysfunction in Type 2 Diabetes via Regulation of Mitochondrial Activity
Israel Olapeju Bolanle, Florah Tshepo Moshapa, Gillian A. Durham…·Timothy M. Palmer
This study identifies JAK/STAT and MAPK/ERK pathways as regulators of mitochondrial dysfunction in HSVSMCs from T2DM patients, suggesting therapeutic targets for preventing saphenous vein graft failure.
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