Loss of Brg1 promotes seizure development via GABAergic system disruption
Roberto Pagano, Karim Abu Nahia, Amber Declève, Dorota Stadnik, Justyna Zmorzyńska, Remigiusz Adam Serwa, Daniëlle Copmans, Jacek Jaworski
This study shows that reduced Brg1 function in zebrafish leads to seizure-like behavior through disruption of the GABAergic system and increased neuronal activity.
bioRxiv · Feb 26, 2026 · PreprintNeuroscience