Karim Abu Nahia

This study shows that reduced Brg1 function in zebrafish leads to seizure-like behavior through disruption of the GABAergic system and increased neuronal activity.

The paper uses scRNA-seq to analyze zebrafish heart development, identifying 18 cell populations and two genes critical for pacemaker function and heart rate regulation.

The paper profiles the transcriptome of the zebrafish atrioventricular canal to identify molecular signatures of pacemaker and valve mesenchyme, revealing conserved features with mammalian AV node and cardiac valves.

This study shows that Adar-mediated A-to-I editing is essential for establishing antero-posterior and dorso-ventral axes in zebrafish embryos.

The paper analyzes transcriptomic and chromatin accessibility changes in zebrafish cardiomyocytes during heart development to identify key regulatory networks and their disruption in mutant lines.